This oversight has resulted in a significant gender gap in healthcare, with women facing different symptoms, causes, and prevalence of various diseases compared to men. Medications and medical devices may also exhibit different efficacy and side effects depending on sex. Women report higher rates of adverse events and fatalities from approved medicines compared to men.
Furthermore, conditions that predominantly affect women are often understudied, underinvested, and underestimated. Consequently, only a small fraction of healthcare research and development targets women's health issues.
This disparity translates into economic costs. A report by the World Economic Forum (WEF) and the McKinsey Health Institute (MHI) estimates that closing the male-female health gap could boost global GDP by at least $1 trillion annually by 2040. This would be achieved through increased workforce participation, reduced lost hours, and enhanced productivity.
Asking the right questions about sex-based differences in disease presentation, causes, and outcomes is essential for closing the health gap. This includes investigating why women experience more chronic pain, have higher mortality rates after heart attacks, and face disparities in care.
In the United States, McKinsey Health Institute found that conditions predominantly affecting women often have higher co-payment requirements. Such practices, even if unintentional, can significantly impact access to care.
Improving service delivery for women, including developing sex-appropriate guidelines for screening and care, can enhance overall performance and health outcomes.
In Canada and the United Kingdom, only 5.9% of grants awarded between 2009 and 2020 focused on female-specific outcomes or women's health. In the United States, conditions that disproportionately affect women, such as migraines, are underfunded relative to their disease burden.
Closing the health gap requires increased investment in understanding sex-based differences and female-specific conditions to address unmet needs.
By addressing the health gap, societies can improve the well-being of women, boost economic growth, and create a more equitable and inclusive healthcare system for all.
About the Authors: Lucy Perez is a senior partner in McKinsey Company's Boston office and co-leader of health equity at the McKinsey Health Institute. Tracy Francis is a senior partner and the Chief Marketing Officer of McKinsey Company.