March 21 (Reuters) - Wall Street opened lower on Friday

as investors continued to navigate the complex landscape of

tariffs, with FedEx becoming the latest firm to adjust its

annual projections due to economic uncertainties.

At 09:30 a.m. ET, the Dow Jones Industrial Average

fell 324.31 points, or 0.77%, to 41,629.01, the S&P 500

lost 44.29 points, or 0.78%, to 5,618.60 and the Nasdaq

Composite lost 171.73 points, or 0.97%, to 17,519.89, at

the opening bell.