March 4 (Reuters) - GSK said on Monday a new
formulation of its HIV prevention and treatment drug could
potentially be administered at least every four months, an
improvement from the previous requirement of dosing every two
months.
Data on the ultra-long-acting cabotegravir was presented at
the Conference on Retroviruses and Opportunistic Infections by
GSK's HIV-focused unit, ViiV Healthcare, which plans to conduct
large-scale clinical trials later this year.
The drug is among a dozen significant product releases that
GSK anticipates in the coming years. The company has shifted its
HIV focus to long-acting treatments and prevention therapies,
amid a series of upcoming patent expiries and litigations.
"This new formulation of cabotegravir with a higher
concentration and at least double the half-life puts us on the
path toward delivering dosing every four months for HIV
treatment and PrEP (pre-exposure prophylaxis)," said Kimberly
Smith, head of Research and Development at ViiV, in a statement.
GSK is also targeting to bring the first ultra-long-acting
medicine for the prevention of HIV in 2026, followed by an
ultra-long-acting HIV treatment medicine in 2027.
Pfizer ( PFE ) and Shionogi ( SGIOF ) hold minority stakes in
GSK's ViiV Healthcare business.
Strong sales of medicines for HIV, the virus that causes
AIDS, drove GSK's growth last year, contributing about 21% of
total revenue.